Françoise Van Bambeke Selected Research

RX-P873

8/2015

RX-P873, a Novel Protein Synthesis Inhibitor, Accumulates in Human THP-1 Monocytes and Is Active against Intracellular Infections by Gram-Positive (Staphylococcus aureus) and Gram-Negative (Pseudomonas aeruginosa) Bacteria.

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Françoise Van Bambeke Research Topics

Disease

56	Infections 01/2024 - 07/2002
14	Cystic Fibrosis (Mucoviscidosis) 02/2024 - 04/2009
7	Pneumonia (Pneumonitis) 05/2021 - 02/2008
6	Healthcare-Associated Pneumonia 01/2017 - 08/2006
5	Critical Illness (Critically Ill) 07/2022 - 01/2015
4	Respiratory Tract Infections (Respiratory Tract Infection) 01/2020 - 02/2008
4	Peritonitis 10/2018 - 11/2009
3	Thrombocytopenia (Thrombopenia) 01/2024 - 11/2019
3	Soft Tissue Infections 05/2021 - 01/2004
3	Bacterial Infections (Bacterial Infection) 04/2020 - 11/2011
3	Necrosis 01/2017 - 08/2005
2	Intraabdominal Infections 07/2022 - 10/2018
2	Septic Shock (Toxic Shock Syndrome) 07/2022 - 01/2019
2	Phototoxic Dermatitis (Phototoxicity) 01/2019 - 01/2009
2	Persistent Infection 01/2017 - 06/2010
2	Pseudomonas Infections 10/2016 - 01/2015
2	Bacterial Pneumonia 01/2016 - 12/2015
2	Chronic Bronchitis 01/2015 - 09/2014
2	Staphylococcal Infections 06/2010 - 06/2010
2	Bacteremia 03/2008 - 08/2006
2	Alzheimer Disease (Alzheimer's Disease) 01/2003 - 12/2002
1	Cerebral Ventriculitis 12/2023
1	Endocarditis 06/2023
1	Candidiasis (Moniliasis) 12/2022
1	Invasive Candidiasis 12/2022
1	Candidemia 12/2022
1	Inflammation (Inflammations) 01/2022
1	Urinary Tract Infections (Urinary Tract Infection) 11/2021
1	Drug-Related Side Effects and Adverse Reactions 05/2021

Drug/Important Bio-Agent (IBA)

44	Anti-Bacterial Agents (Antibiotics)IBA 02/2024 - 07/2002
10	Linezolid (Zyvox)FDA Link 01/2024 - 04/2009
9	FluoroquinolonesIBA 11/2021 - 07/2002
8	temocillinIBA 12/2023 - 03/2012
8	oritavancinIBA 12/2015 - 01/2004
7	Gentamicins (Gentamicin)FDA LinkGeneric 11/2021 - 08/2005
6	Vancomycin FDA LinkGeneric 01/2022 - 01/2004
6	MacrolidesIBA 01/2017 - 02/2008
5	Daptomycin FDA Link 06/2023 - 04/2009
5	Ciprofloxacin (Cipro)FDA LinkGeneric 11/2021 - 06/2009
5	Moxifloxacin (Avelox)FDA Link 06/2020 - 07/2004
5	telavancin FDA Link 12/2015 - 10/2004
4	LactamsIBA 06/2023 - 03/2012
4	Meropenem (Merrem)FDA LinkGeneric 01/2021 - 01/2015
4	QuinolonesIBA 01/2019 - 06/2005
4	LipoglycopeptidesIBA 12/2015 - 08/2006
3	Peptides (Polypeptides)IBA 06/2023 - 12/2002
3	Rifampin (Rifampicin)FDA LinkGeneric 11/2022 - 04/2009
3	EnzymesIBA 01/2022 - 12/2015
3	finafloxacinIBA 11/2021 - 07/2011
3	Ceftazidime (Fortum)FDA LinkGeneric 01/2021 - 05/2015
3	AcidsIBA 01/2019 - 01/2004
3	delafloxacinIBA 01/2019 - 06/2013
3	Fusidic Acid (Fucithalmic)IBA 01/2018 - 04/2009
3	KetolidesIBA 01/2017 - 02/2008
3	telithromycin (Ketek)FDA Link 01/2016 - 02/2008
3	dalbavancinIBA 12/2015 - 10/2004
3	Clindamycin (Cleocin)FDA LinkGeneric 03/2011 - 04/2009
3	Oxacillin (Prostaphlin)FDA LinkGeneric 04/2009 - 02/2007
3	GlycopeptidesIBA 08/2006 - 01/2004
3	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 04/2006 - 08/2005
2	Ceftaroline FDA Link 06/2023 - 03/2013
2	Nafcillin FDA LinkGeneric 06/2023 - 12/2017
2	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 11/2021 - 03/2011
2	Ampicillin (Omnipen)FDA LinkGeneric 11/2021 - 07/2004
2	ceftazidime drug combination avibactamIBA 01/2021 - 11/2018
2	Oxazolidinones (2 Oxazolidone)IBA 11/2019 - 01/2018
2	Tigecycline (Tygacil)FDA Link 10/2018 - 04/2009
2	solithromycinIBA 01/2016 - 11/2014
2	Proteins (Proteins, Gene)FDA Link 06/2009 - 01/2003
2	quinupristin-dalfopristin (Synercid)FDA Link 04/2009 - 04/2009
2	ThymidineIBA 04/2009 - 04/2009
2	beta-LactamsIBA 01/2009 - 01/2007
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2004 - 06/2004
1	DNA (Deoxyribonucleic Acid)IBA 02/2024
1	poly(beta-D-mannuronate) lyase (D-mannuronate lyase)IBA 02/2024
1	Expectorants (Mucolytics)IBA 02/2024
1	Deoxyribonuclease I (Nickase)IBA 02/2024
1	CathelicidinsIBA 06/2023
1	PolyenesIBA 12/2022
1	EchinocandinsIBA 12/2022
1	AzolesIBA 12/2022
1	pyrimidineIBA 12/2022
1	Levofloxacin (Levaquin)FDA Link 11/2022
1	lyticaseIBA 01/2022
1	AlbuminsIBA 01/2022
1	CellulaseIBA 01/2022
1	Peptide Hydrolases (Proteases)FDA Link 01/2022
1	Subtilisins (Subtilopeptidase A)IBA 01/2022
1	Nitrofurantoin (Macrodantin)FDA LinkGeneric 11/2021
1	Imipenem FDA Link 01/2021
1	Amikacin (A.M.K)FDA LinkGeneric 01/2021
1	Colistin (Coly-Mycin)FDA Link 01/2021
1	Sulfamethoxazole FDA LinkGeneric 01/2021

Therapy/Procedure

10	Therapeutics 06/2023 - 11/2009
2	Duration of Therapy 01/2024 - 05/2021
2	Arthroplasty 01/2021 - 01/2020
1	Intravenous Administration 07/2022
1	Replacement Arthroplasty 01/2022
1	Debridement 01/2022
1	Off-Label Use 05/2021